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コロナ感染症対策としての男性への女性ホルモン投与テスト [世相(新型コロナ肺炎関連)]

5月8日(金)

まじめな話、アメリカで、コロナ感染症対策として、男性への女性ホルモン投与テストが始まる。

ニューヨークでは、110人の参加者(18歳以上の男性または55歳以上の女)を、エストロゲンパッチを受ける群と受けない群に分けて比較実験(11月に結果)。

ロサンゼルスでは、40人の男性(18歳以上)にプロゲステロンの注射を5日間行う(9月)。
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Testing Estrogen on Men with COVID-19
COVID-19: Updates
by Suzanne B. Robotti
last updated: May 2, 2020

Will turning men into women save their lives? Of course, I am speaking facetiously. Doctors on the front line have noticed that women seem to survive COVID-19 better than men. A new report estimates that twice as many women survive as men. This has generated a debate among scientists: What is it that women have and men don’t?
The answer that two different scientific teams have come up with is estrogen and progesterone. Perhaps these “women’s hormones” offer some protective veil? There is no theory offered as to why that would be.

Pumping estrogen and the combination of estrogen/progesterone into women has had some pretty bad results in the past. The Women’s Health Initiative (WHI) showed in 2002 that HRT (hormone replacement therapy) that combined estrogen and progestin was associated with an increased risk of breast cancer, some increased risk of cardiovascular disease, and more harm than benefit overall. Two years later a different arm of the same study showed estrogen alone increased the risk of stroke.

And thirty years before the WHI study, pregnant women who had a history of miscarriage were prescribed massive amounts of synthetic estrogen, diethylstilbestrol (DES). The outcome wasn’t good, DES did not increase successful pregnancies and it had the adverse effect of causing malformations in the developing of the fetus’ reproductive system and cancers in some of the offspring. The women who had been given the DES directly (the mothers) suffered breast cancer at higher rates than other women.

So there is reason to be concerned that pumping estrogen into anyone might not be a great idea. Men can have breast and other cancers, and DES has never been given to men directly, so the effect on them, and their offspring, is unknown.

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